Syringic acid: A promising phenolic phytochemical with extensive therapeutic applications
Abstract
Background: Phenolic acids are bioactive phytochemicals that play a pivotal role in human health. Syringic acid is one of the most common phenolic acids and belongs to the class hydroxybenzoic acid. It is predominantly present in olives, dates, grapes, walnuts, radishes, and pumpkins. The chemical structure of Syringic acid consists of a benzene ring with a hydroxyl (-OH) group and two methoxy (-OCH3) groups attached to the ring. The methoxy groups’ presence on the aromatic ring at positions 3 and 5 is responsible for conferring the therapeutic properties of Syringic acid. This review aims to explore the natural sources, structure, biosynthesis, bioavailability, and therapeutic effects of Syringic acid. Syringic acid exhibits a wide range of pharmacological properties, including antioxidant, anti-inflammatory, hepatoprotective, cardioprotective, neuroprotective, antimicrobial, antidiabetic, and antiendotoxic properties.
Keywords: Phytochemicals, Syringic acid, Bioactive compounds, Therapeutic effects
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