Effects of taurine intake on serum lipids in young women

Authors

  • Sadako Matsui Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan
  • Chizuko Maruyama Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan
  • Hiroe Arai Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan
  • Sachie Hashimoto Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan
  • Tamami Asakusa Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan
  • Hiroshi Yoshida Department of Laboratory Medicine, The Jikei University School of Medicine, 163-1, Kashiwashita, Kashiwa-shi, Chiba, 277-8567, Japan
  • Toshitsugu Ishikawa Department of Nutrition and Life Science, Faculty of Applied Bioscience, Kanagawa Institute of Technology, 1030, Shimo-ogino, Atsugi, Kanagawa, 243-0292, Japan

DOI:

https://doi.org/10.31989/ffhd.v5i5.180

Abstract

Background: Taurine is an abundant amino acid in human cells, promoting ocular and biliary health, which is also used to treat congestive heart failure, hypertension, and hepatitis. Recently, taurine-enriched energy drinks have become popular with young adults, but the effects of taurine on serum lipids in young adults are unknown.

Objective: We studied the influence of oral administration of taurine on serum lipid levels in healthy young women.

Methods: Ten healthy young women with a mean body mass index of 20.0kg/m2, apolipoprotein E (apoE) phenotype 3/3 and normal menstrual cycles participated. Each subject was instructed to orally ingest 1g of taurine powder after each meal (3g/day) in addition to their usual diets during one menstrual cycle. Before and at the end of taurine intake, physical measurements and blood collection were performed in the morning after a 12-h fast, and 3-day weighted dietary records were obtained. Concentrations of serum lipids, apolipoproteins, and fatty acids in the serum phospholipid fraction were measured.

Results: The subjects showed good compliance with taurine intake and none reported adverse effects during the experimental period. After taurine intake, concentrations of total cholesterol, low density lipoprotein cholesterol (LDL-C), free cholesterol, and apolipoprotein B (apoB) increased (p<0.05), while phospholipids tended to increase (p=0.051). Fatty acids in the serum phospholipid fraction also significantly increased (p<0.05). However, triglyceride, remnant-like particle cholesterol, remnant-like particle triglyceride, apoE, the apolipoprotein A-1 (apoA- 1)/apoB ratio and the LDL-C/apoB ratio were unchanged. Furthermore, body weight was significantly increased (p<0.01), but did not correlate with changes either in serum lipids or nutrient intakes.

Conclusion: These results suggest that high taurine intake affects lipoprotein metabolism and increases serum lipids in slightly lean young women.

Key Words: Taurine, slightly lean young women, serum lipids, remnant lipoprotein, fatty acids of the serum phospholipid fraction.

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Published

2015-05-29

Issue

Vol. 5 No. 5 (2015): May 2015

Section

Research Articles

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