Bioactive Compounds in Health and Disease – Focus on Rutin
DOI:
https://doi.org/10.31989/bchd.v6i10.1145Abstract
The flavonoid rutin was first isolated from rue (Ruta graveolens L.) and is used therapeutically as a capillary stabilizing and vasoprotective agent to reduce capillary fragility, although no health claims have been approved in the EU. This article briefly focuses on physicochemical properties, occurrence in foods and oral bioavailability of rutin, with emphasis on human studies. According to the available information, rutin can be considered a promising bioactive compound, despite the paucity of clinical trials. In addition to its therapeutic relevance in pathological and pathophysiological conditions, dietary rutin can also contribute to improve the physiological status of the organism in healthy subjects, thus preventing the onset of non-communicable chronic degenerative diseases.
Keywords: Flavonoids; polyphenols; phenylpropanoids; bioactive phytochemicals; biological activity; oral bioavailability pharmacokinetics; safety; rutin
Veröffentlicht
Ausgabe
Rubrik
Lizenz
Copyright (c) 2023 FFC/Bioactive Compounds in Health and Disease
Dieses Werk steht unter der Lizenz Creative Commons Namensnennung - Nicht-kommerziell 4.0 International.
Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License.
This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged.
By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained.