Bioactive Compounds in Health and Disease – Focus on Rutin
DOI:
https://doi.org/10.31989/bchd.v6i10.1145Abstrakt
The flavonoid rutin was first isolated from rue (Ruta graveolens L.) and is used therapeutically as a capillary stabilizing and vasoprotective agent to reduce capillary fragility, although no health claims have been approved in the EU. This article briefly focuses on physicochemical properties, occurrence in foods and oral bioavailability of rutin, with emphasis on human studies. According to the available information, rutin can be considered a promising bioactive compound, despite the paucity of clinical trials. In addition to its therapeutic relevance in pathological and pathophysiological conditions, dietary rutin can also contribute to improve the physiological status of the organism in healthy subjects, thus preventing the onset of non-communicable chronic degenerative diseases.
Keywords: Flavonoids; polyphenols; phenylpropanoids; bioactive phytochemicals; biological activity; oral bioavailability pharmacokinetics; safety; rutin
Opublikowane
Numer
Dział
Licencja
Any manuscripts or substantial parts of it, submitted to the journal must not be under consideration by or previously published in any other journal or citable form. Authors are required to ensure that no material submitted as part of a manuscript infringes existing copyrights or the rights of a third party. In submitting one's article in any form, the author has assigned the FFC publishing rights and has agreed to an automatic transfer of the copyright to the publisher. This is so that the FFC may create print option journals, for example, at the FFC’s discretion. If the author wishes to distribute their works by means outside of the FFC, for example within their community, they will have to place a request.
Correspondence concerning articles published in Functional Foods in Health and Disease is encouraged. While derivative works (adaptations, extensions on the current work, etc.) are allowed, distribution of the modified material is not allowed without permission from the FFC.